Commentary about treatment of male hypogonadism with clomiphene citrate compare to treatment with testosterone

Clomiphene citrate (CC) is a selective estrogen receptor modulator and antagonist. It was introduced into clinical medicine in 1967 for the treatment of female infertility. CC has also been explored off-label use male infertility hypogonadal symptoms. We want to comment discuss medical literature on its contribution hypogonadism. The main goal commentary mechanism action when it can be used hypogonadism instead Testosterone which FDA approved. [1,2]. increases level blood similar gel. improves symptoms as well. difference with that preserves sperm production fertility if desired patients secondary/tertiary safety compared regarded an effective therapy specific who suffer from factor complain More studies are needed further validate CC's efficacy